L’Oréal’s Skinbetter Science Launches Volume-restoring Facial Serum


Ten years after AlphaRet Overnight Cream, Skinbetter Science might have its next hero.

The physician-dispensed brand, which was acquired by L’Oréal in 2022, has launched its Ampra Volumizing Macro HA Serum. Priced at $180, the serum is powered by a hero “Hyasinc” molecule, wherein alpha-lipoic acid is structurally bonded to hyaluronic acid to help the latter penetrate skin deeply enough to boost the look of facial volume.

The molecule has been in development for roughly as long as Skinbetter Science has been part of L’Oréal’s portfolio.

“Everybody is looking for more facial volume, but we know that right now, even more people are looking for volume due to fat loss from using GLP-1s,” said Geneviève Bibeau, general manager of Skinbetter Science at L’Oréal. “So [this product] has been a big request from aesthetic providers.”

The launch is expected to generate high seven-figure sales during its first year on the market, where it will be available via Skinbetter Science’s primary channel — in nearly 8,000 clinics and physicians’ offices in the U.S. — as well as direct-to-consumer.

A clinical study of the serum indicated that, with twice-daily use over the course of 12 weeks, Ampra improved the look of skin sagging by 23 percent, and improved the appearance of fine lines by 20 percent. A consumer perception study indicated 98 percent of participants reported plumper-looking after 12 weeks of use.

Ampra is Skinbetter Science’s most significant launch since its first product, AlphaRet Overnight Cream, was introduced in 2016 as a nonprescription retinoid for customers whose skin can’t tolerate traditional retinoids.

According to Bibeau, Skinbetter Science ranks as the number-three professional skin care brand in the U.S., and has a customer base that is 75 percent Millennials and Gen X. Next year, the brand looks to expand beyond North America into markets that could include China, Australia, the U.K and more.

“We’re preparing for the international launch; we want to continue to grow AlphaRet, because so many consumers still don’t know the product, and [launching Ampra] is also a big focus for the year. We believe these two products combined are going to be the secret recipe for us to reach the number-two [professional brand] position,” said Bibeau, adding that the brand will put Ampra front and center via a presentation and display at the American Academy of Dermatology convention taking place later this month.

Professional skin care is booming, particularly in the U.S. as customers increasingly look to maximize skin “longevity” through both effective treatment and preventative products. The category is also a key area of focus for L’Oréal, which is the biggest beauty company in the world and counts SkinCeuticals, La Roche-Posay, Vichy Laboratories and CeraVe alongside Skinbetter Science in its dermatological division.



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