6 Best GLP-1 Nutrition Support Supplements For 2026

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Our editors have researched and taken clean supplements for years. These are our picks for supplements with quality, third-party-tested ingredients to help support your overall wellness while taking GLP-1 medications.

Once exclusively considered a treatment for diabetes, glucagon-like peptide-1 (GLP-1) medications like Ozempic and Mounjaro have hurled into the cultural zeitgeist for weight loss management. For many people, these medications are life-altering — but they can also leave you with nutritional gaps. Because they can reduce caloric consumption, you might be missing out on necessary nutrients. That’s where GLP-1 nutrition support supplements come into play, providing you with a more complete diet.

What are GLP-1 nutrition support supplements?

These supplements are designed to help address common nutritional considerations while taking GLP-1 medications, including protein intake, hydration, digestive support, and maintaining energy levels. Many people taking GLP-1s also experience dehydration, so many of our favorite supplements replace those much-needed electrolytes as well. As always, you should consult your healthcare provider before adding any supplement to your routine.

What nutrients are important while taking GLP-1 medications?

Common nutritional gaps include protein, fiber, electrolytes, probiotics, digestive enzymes, vitamins, and minerals. And again, this all depends on your diet, and it’s best to consult your healthcare provider to find supplements that will be the most beneficial.

Why are clean, third-party tested supplements important?

People are starting to embrace this burgeoning GLP-1 era, but with so many supplements on the market, choosing the right one for you can feel overwhelming. That’s why we appreciate brands with clean formulas that are tested and approved by third parties to verify their purity and efficacy.

Our criteria:

After researching, corresponding with brands, and combing through customer reviews, our editors have chosen our favorite brands offering GLP-1 nutrition support supplements to complement your wellness routine. We update this list regularly with new, emerging favorites, and all of our picks are evaluated to meet the following criteria:

SCIENCE-BACKED | GLP-1 nutrition support supplements are becoming increasingly popular as more people look for ways to support muscle maintenance, digestion, hydration, and nutrient intake while taking GLP-1 medications. We’ve prioritized brands that have scientific and clinical backing.
THIRD-PARTY TESTED | Each brand uses high-quality ingredients without synthetic fillers, artificial flavors, dyes, parabens, or unnecessary additives. The options on this list offer third-party testing so you know what you’re taking.

Your health is crucial, and there are so many products our editors love that have made us feel stronger, more energetic, and better overall. For more information, review our guides to the best women’s multivitamins, protein powders, electrolytes, and probiotics to support your health.

1. Thorne

Best For | Complete support system
Key Ingredients | Basic Nutrients 2/Day: vitamins A, B12, C, D3, K1, and K2, folate, zinc, magnesium, calcium; Complete Biotic: Bacillus subtilis, heat-treated Bifidobacterium longum, PreforPro; Amino Complex: L-Cystine, L-Histidine, L-Isoleucine, L-Leucine, L-Lysine, L-Methionine, L-Phenylalanine, L-Threonine, L-Tryptophan, L-Tryosine, L-Valine; Daily Electrolytes: calcium, chloride, magnesium, potassium, sodium
Prices starting at | $161 for a one-month supply

Thorne’s complex GLP-1 Support Stack system comprises four products: Basic Nutrients 2/Day, two capsules taken daily to support your general health; Complete Biotic, an orange-flavored powder that acts as a prebiotic, probiotic, and postbiotic; Amino Complex, a berry- or lemon-flavored powder to help build lean muscle; and a variety pack of Daily Electrolyte powders in blood orange, mango limeade, and watermelon. When combined, this monthly supply provides comprehensive support for people taking GLP-1 medications for weight loss or type 2 diabetes, or for those on a weight loss journey.

Thorne products are third-party tested and derived from natural flavors and colors. All nutritional supplements are made in the United States, in the company’s manufacturing space in Summerville, South Carolina. Subscriptions are available, and you can save up to 20 percent when you schedule recurring deliveries every two weeks, four weeks, 45 days, two months, three months, or four months.

Customer Review | “It was feeling very groggy and sore all over and began taking this Stack which cured all the side effects so am delighted!!!” – Carolyn S. (Read more reviews.)

Four Thorne supplement products are displayed against a light pink background, including Amino Complex, Daily Electrolytes, Complete Biotic, and a bottle of FloraMend Prime Probiotic.

A person pours capsules from a white supplement bottle into their hand, wearing a black shirt with a large white "T" printed on it.

2. Moon Juice

Best For | Bioavailable formulas
Key Ingredients | SuperHair: vitamins A, C, D3, E, B1, B2, B3, B5, B6, and B12, folate, biotin, iron, iodine; Mini Dew: calcium, magnesium, zinc, selenium, copper, chloride, sodium, potassium, ionic trace materials, boron, malic acid; Magnesi-Om: citrate, gluconate, acetyl taurinate, L-theanine
Prices starting at | $129 for a one-month supply

Our team often recommends Moon Juice for their bioavailable formulas and 100 percent traceable ingredients. Their transparency is commendable, and we appreciate how they use organic materials and reusable or compostable packaging when possible. This particular support stack meets that criteria, while also focusing on key concerns GLP-1 users face. SuperHair is a four-capsule supplement dose designed to improve the thickness and strength of hair, Mini Dew is an electrolyte powder (available in watermelon, pomelo, or flavorless), and Magnesi-Om is another powder to address mood and digestive regularity.

This support stack is only sold as a one-time purchase, but you can order multiple packs at a time if you need to stock up. The brand doesn’t have suggested timing for taking these supplements, though they recommend mixing one teaspoon of the magnesium powder into water at night for extra sleep support.

Customer Review | “Love Moon Juice!! Always have, they have the greatest products!” – Valerie (Read more reviews.)

A brown bottle labeled "SuperHair" by Moon Juice, containing capsules, with four capsules lying on a light surface in front of the bottle.

A brown jar labeled “Mini Dew” by Moon Juice sits next to a glass of pink liquid on a light-colored surface.

3. Codeage

Best For | Standalone GLP-1 nutritional support
Key Ingredients | Lion’s mane, PEA, bovine colostrum, shilajit resin extract
Prices starting at | $40 for a one-month supply

For a one-and-done formula to fill your nutritional gaps, consider this best-seller from Codeage. True to its name, GLP-Harmony Companion+ uses ingredients like lion’s made, PEA, and colostrum to complement your wellness routine. And while ingredients are sourced internationally, the company manufactures their supplements in a cGMP-certified facility in the U.S.

This product is part of Codeage’s fourth and final pillar, Systemic Balance, in what they refer to as the Longevity Code. The brand recommends taking two capsules per day with 8 ounces of water 30 minutes before your largest meal, or as instructed by your healthcare provider. If you’re looking for a more affordable supplement, this standalone option is just over $1 per serving.

Customer Review | “I think this is an excellent option for anyone seeking assistance with digestive health. It definitely has multiple benefits, leaving me feeling more energized and healthy. Codeage is very trustworthy with their super clean ingredients and science backed products.” – Verified Purchaser (Read more reviews.)

A container of Codeage GLP-Harmony Companion+ dietary supplement capsules is displayed on a stone slab with blurred flowers and leaves in the background.

A white container labeled "GLP-Harmony Companion+ Trim & Glow+" by Codeage surrounded by colorful, translucent bubbles and soft pastel shapes.

4. Midi Health

Best For | Nausea
Key Ingredients | Vitamins D3, B6, and B9, calcium, ginger, prebiotic fiber, digestive enzymes
Prices starting at | $40 for a one-month supply

MidiHealth is on a mission to support women during the midlife stage (in their 30s to 50s). Their tagline is “Made for women, by women,” and they also have clinicians on-hand to craft personalized care plans for their customers. Virtual visits and insurance coverage is available, and their Daily GLP-1 Support supplement prioritizes one of the worst side effects of taking this medication: nausea. Ginger and vitamin B6 are key ingredients for nausea relief, and MidiHealth’s formula rounds out their care with a bone-building, nutrient-replenishing formula.

These capsules are best for women taking GLP-1s who are struggling with nausea, stomach problems, low energy, and brain fog. The brand says to take two capsules per day, or as recommended by your healthcare provider. If you’re still experiencing nausea, consider asking your doctor about increasing your dose. Loyal customers will also appreciate the company’s “Give $10, Get $10” lets you get $10 off each time you successfully refer a friend.

Customer Review | “I started this support product to assist with my GLP1 injections. If you feel nauseous, if you have bathroom habits that changed, this product is the answer.” – Christy L. (Read more reviews.)

A bottle labeled "Midi Daily GLP-1 Support" with nutritional claims is shown on a blue background, alongside two white capsules.

A clear glass of sparkling water with two white capsules placed beside it on a light blue background.

5. IM8

Best For | Powder supplement
Key Ingredients | B-complex, CoQ10, BCAAs, MSM, vitamins C and D, zinc, selenium, 10 billion CFU probiotics, prebiotics, and postbiotics
Prices starting at | $78 for a three-month supply (with a subscription)

The brainchild of biotech company Prenetics and former professional soccer player David Beckham, IM8 has developed an all-in-one supplement packed with a whopping 90 “nutrient-rich ingredients,” including B vitamins, CoQ10, and prebiotic fiber. Mixed into water, the powder flavors include acai and mixed berries, lemon and orange, and mango and passionfruit. Or if you’re interested in testing out all of them, IM8 sells a variety pack. The brand estimates that this one tasty drink can replace 16 supplements, and can support your energy, digestion, and sleep.

This product is designed to work as an essential vitamin and nutrient mixture, but the brand says it’s ideal for anyone taking GLP-1 medications. “GLP-1 drugs change how you eat. That changes everything about what your body receives,” IM8 shared in an article on their website.

As part of their commitment to eco-friendly packaging, IM8 uses 100 percent polyethylene terephthalate (PET) for plastic jars and 100 percent recycled polypropylene (PP) for lids. Plus, all jars are refillable and reusable, so you don’t have to receive a new one each time. When you make your first IM8 purchase, you’ll receive 35 percent off your order and get welcome gifts valued at $72. The delivery includes five extra single-serve sachets of the supplement, a storage box, mixer, and red cup.

Customer Review | “I feel so much better when taking IM8. It makes me feel rejuvenated and vital. I actually think my brain fog is subsiding.” – Carol (Read more reviews.)

A hand holds a red shaker bottle labeled "IM·8" next to supplement packets, a box, a glass of red drink, and a small handheld frother, all on a white background.

A man with tattoos in a grey sweatshirt holds a glass of red beverage, leaning on a counter next to a red box labeled "IM-8" and red packets.

6. Ora

Best For | Support stack with protein powder
Key Ingredients | So Lean & So Clean: Organic pea protein, organic acai, digestive enzymes; Modern Multi: Lutein and zeaxanthin from marigold, organic quinoa sprouts extract, vitamin K2 from chickpeas; Trust Your Gut: Organic Jerusalem artichoke, Lactobacillus acidophilus LA-14, Bifidobacterium bifidum UABb-10
Prices starting at | $40 per month with a subscription

Another complete system, this one from Ora includes a vegan protein powder with six flavors to choose from, a plant-based multivitamin, and a daily synbiotic with 16 billion CFU and six probiotic strains. Together, along with electrolytes, Ora says these are “science-backed supplements that act as your GLP-1 sidekick, helping you navigate the challenges while maximizing the benefits.”

Because strength training is recommended while taking a GLP-1, Ora is contributing to this area of concern with its flavorful protein powder. After training, mix two scoops into plant milk or a smoothie. Meanwhile, the system’s daily multivitamin works on giving you a boost of energy and filling any additional nutrient gaps with bioavailable ingredients, and it should be taken with your largest meal of the day. Rounding out this collection, the probiotic and prebiotic is a one- or two-capsule dose you can swallow or break open and add to your smoothie.

The thoughtfully designed packaging is one example of their sustainability initiatives. Aluminum tins and foil seals, and a biodegradable scoop are just a few of the eco-friendly materials used to put these products together. Subscriptions are also on the table, and you can save 20 percent when you have new shipments delivered every 30, 45, or 60 days.

Customer Review | “Amazing smooth & delicious formula! Easy to drink and digest with no bloating! Love this protein!” – Kelly N. (Read more reviews.)

A hand holds a scoop of vanilla plant protein powder above an Ora So Lean & So Clean container, with a pile of powder and its reflection on the surface below.

A blue bottle of Ora "Trust Your Gut" pre and probiotic capsules sits on green palm leaves against a clear blue sky.

Katherine J. Igoe is a writer and editor who covers fashion, beauty, and lifestyle, with sustainability at the core of her work. She’s written for The New York Times, The Cut, InStyle, etc., and been a contributing editor at Cosmo and Marie Claire.

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