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We’ve personally used and researched dozens of clean supplements — these are our favorites with functional mushrooms for a variety of benefits. 🍄

I started taking a functional mushroom tincture a few years ago after quitting caffeine — before you ask, yes, I do live in LA — and a friend mentioned that functional mushrooms could be a great replacement to help me focus. I tried a few drops of her tincture and went about my day, half-expecting to feel nothing. Yet, the results were undeniable. I experienced focus and mental clarity without the jitters or anxiety that come with coffee. Needless to say, I was hooked. Ever since, I’ve been keeping an eye on this budding supplement superstar as other benefits are discovered and new formulations emerge.

As more brands explore functional mushrooms and new products appear on the shelves of my favorite specialty grocer, it’s clear that we’re in a mushroomaissance — and we’re only just scratching the surface of what they can do.

What is a functional mushroom? And what are their benefits?

Functional mushrooms are an increasingly popular subset of the vast fungi family — consider them cousins of the ones you sauté in butter. They’ve become a wellness buzzword for their transformative benefits — not to mention the inventive ways to take them, like as tinctures, in chocolates, or as coffee-alternative drinks. Functional mushrooms are packed with bioactive compounds that deliver a whole lot of nutrients and adaptogens to your daily routine. Adaptogens – natural substances that help the body manage stress and maintain balance — work by modulating the body’s stress response and supporting homeostasis, which is crucial for overall health and well-being. In other words, functional mushrooms help support your body’s natural process to let you operate at your best and prevent health issues down the line.

In order to make the most of their benefits, farming functional mushrooms has to be an exact science and a careful art. To get the most out of them, these natural superfoods are typically grown in controlled environments and harvested at their peak to maximize their nutritional value. It’s like picking rare-blooming flowers for perfume when their smell is the strongest — same principle, but for superfoods. Then, the mushrooms are dried and processed to extract their beneficial compounds. This extraction process isolates the bioactive compounds, which are then most often concentrated into powders.

There are many different types of functional mushrooms — and each with its own specific benefits, such as:

• Reishi (Ganoderma lucidum): Reishi is the chill mushroom. Known for its calming effects, it is an excellent choice for stress relief and better sleep. It also contains beta-glucans and triterpenes to enhance the immune system’s ability to fight off infections and reduce inflammation.
• Lion’s Mane (Hericium erinaceus): Lion’s Mane is quite literally brain food. A jolt of electricity to your brain, it supports cognitive function with compounds that stimulate the production of nerve growth factor (NGF), which is essential for brain health. It’s also great for short-term goals, like focus support. Regular consumption of Lion’s Mane can help improve memory, concentration, and overall cognitive performance, making it a good daily boost for your brain.
• Chaga (Inonotus obliquus): You’ve probably seen “chagaccinos” in your local wellness coffee shops, combining chaga mushrooms with coffee for an antioxidant-rich version of your daily cup of Joe. Antioxidants, which help protect cells from damage caused by free radicals, making Chaga a great option for aging support and promoting overall cellular health. Its high antioxidant content also supports the immune system, helping the body fend off illnesses.
• Cordyceps (Cordyceps sinensis): Fun fact: The 1993 Chinese Olympic running team broke records by incorporating cordyceps into their diet, making people start paying attention to this ancient functional mushroom. It’s a natural energy drink, boosting athletic performance by enhancing physical endurance and energy levels. It works by stimulating the body’s primary energy currency, improving oxygen utilization and stamina, which makes it perfect for athletes and those looking to boost their exercise performance — or anyone who wants to feel more energized without caffeine.
• Maitake (Grifola frondosa): A potent source of vitamin D, this mushroom (also known as hen-of-the-woods), supports everything from bone health to metabolic function. Maitake mushrooms regulate your body’s blood sugar levels, and the beta-glucans they contain activate and enhance the immune system’s ability to respond to infections.
• Turkey Tail (Trametes versicolor): Turkey Tail mushrooms are another powerhouse for immune support. They are rich in ingredients known to boost the immune system and have been studied for their potential role in supporting cancer treatment. These mushrooms are also beneficial for gut health since they’re packed with prebiotic properties.

What’s the best way to take functional mushrooms?

Like any supplement, functional mushroom supplements combine the benefits of mushrooms with other ingredients to target specific concerns and boost their effectiveness. Incorporating functional mushrooms into your daily routine can boost your immune system, enhance cognitive function, support graceful aging and improve physical endurance. Especially if you combine multiple mushroom extracts together — in one do-it-all supplement or a lineup of capsules, powders, and tinctures.

Dosing functional mushroom supplements varies based on the type of mushroom and the desired effect. For general wellness, a daily dose ranging from 500 to 3000 milligrams of mushroom extract is the standard. Combining different types of functional mushrooms can create surprising synergistic effects. For example, try blending Lion’s Mane for cognitive support with Reishi for stress relief and immune support. Always start with a lower dose to assess your body’s response and consult with a healthcare provider to determine the best regimen tailored to your specific needs and health goals. Plus, many of the brands below do the work of combining functional mushrooms for you in easy-to-take supplements so you can feel specific effects. In fact, we’ve chosen formulations that are safe and effective for our guide below.

Our criteria:

Our editors have personally used and loved the best clean supplements on the market. For this list, we’ve compiled our favorite mushroom supplements without any fillers that are thoughtfully harvested and formulated, too. We add new favorites to this list when they meet the below qualifications.

• CLEAN INGREDIENTS | The supplements below use natural ingredients with no fillers so you’re getting the purest product. All of the brands on this list are also thoughtful about farming and cultivation, and refrain from using harsh chemicals in the process.
• THOUGHTFULLY HARVESTED | The mushrooms in these supplements are all thoughtfully farmed and specifically harvested to extract the full potential of their beneficial properties. The mindful farming practices are tailored to preserve the purity of their ingredients.
• GENTLE FORMULATIONS | These supplements are formulated to be gentle on your stomach, and combine functional mushroom types for the best effects. We’ve reviewed the experts behind each brand, whether they’re coming from a holistic, medical, or scientific background.

If you’re looking for more ways to support and supplement your holistic health, check out our magnesium supplement guide, and our guide to the best daily multivitamins.

1. ReNude

Best For | Your morning beverage
Active Ingredients | Wild Foraged Chaga, Organic Peruvian Cacao, Organic Ceylon Cinnamon, Monk Fruit Sweetener
Contains Caffeine | No
Prices Starting At | $30

Want to try a Chagaccino (or Chaga Matcha) at home? Start here. ReNude makes beverage blends to transform your daily beverage routine using functional mushrooms. Sort of like a mushroom mocha, a Chagaccino is a tasty drink that supports immunity, promotes anti-aging, and boosts your energy. The mushroom antioxidants protect the body from free radicals and oxidative stress from the inside. But it’s not just preventative. You also get an immediate boost of endurance, cognitive focus, stress relief, immune support, and anti-aging.

Customer review | “I’ve noticed a huge difference w coffee and gut discomfort after taking chaga for over a week! Absolutely love” – Mia (Read more reviews.)

2. Sunmed

Best For | All-in-one support
Active Ingredients | Maitake, shiitake, lion’s mane, reishi, cordyceps, chaga, turkey tail, white button, black fungus, royal sun
Contains Caffeine | No
Prices Starting At | $40

Supercharge your daily routine with Sunmed’s All-in-One Mushroom Gummies, featuring a powerful blend of 10 adaptogenic mushrooms. These gummies are crafted with premium fruiting body extracts including maitake, shiitake, lion’s mane, reishi, and more, each known for their adaptogenic and nootropic properties. With only two gummies per day, you’ll experience enhanced mood stabilization, better memory and focus, increased energy, immune support, improved stress response, and digestive health. Free from psilocybin, these gummies are formulated for daily use, making it easy for you to incorporate the powerful benefits of functional mushrooms into your diet. 

Customer Review | “I can feel a cognitive difference after 1 bag! I feel sharper, my mood is better and we are on auto renew to keep receiving them.” – Lorrie Culp (Read more reviews.) 

SAVE 30% OFF ALL PRODUCTS WITH CODE SUNMED30.
(EXCLUDES ALREADY DISCOUNTED PRODUCTS.)

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3. Quince

Best For | 100% organic Lion’s Mane
Active Ingredients | Organic Lion’s Mane extract (fruiting body)
Contains Caffeine | No
Prices Starting At | $25

Quince‘s Certified Organic Lion’s Mane is an easy addition to a daily wellness routine for anyone looking to support focus, memory, and mental clarity. Made with 1,000mg of organic Lion’s Mane fruiting body extract per two-serving capsule, this formula is specially crafted to support cognitive function, mental performance, healthy cognitive aging, and balanced mood. It’s also refreshingly no-nonsense: The capsules are housed in a premium glass bottle and are free from fillers, preservatives, and the top 12 major allergens, plus every batch is third-party tested for purity, microbes, and heavy metals in a cGMP-compliant, FDA-registered facility. For only $0.42 per serving, it’s never been easier or more affordable to create a daily brain-health routine!

Customer Review | “Research shows that lions mane can help with cognition and memory, and I have found that this stuff actually works. I’ve been taking it consistently for several months and I definitely notice that I feel more mentally sharp. I’m in perimenopause, so the brain fog is real. This helps.” – Analee T. (Read more reviews.) 

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4. Alice

Best For | Targeted support
Active Ingredients | Dark Chocolate with Lions Mane and Cordyceps (Brainstorm), Cordyceps and Ashwagandha (Happy Ending), Reishi and Magnesium (Nightcap)
Contains Caffeine | Yes
Prices Starting At | $59

Alice in Wonderland fans, this one’s for you. Alice makes it easy to start your journey with mushrooms with simple products that encourage your curiosity and have targeted benefits — focus, sleep, or libido. Their chocolate supplements boost your cognitive function and supplement your wellness routine combining high-quality fruiting-body mushrooms with the best nootropics and adaptogens. Their lineup of three products include: The Brainstorm, for focus, Nightcap, for sleep, and Happy Ending, for libido. Start or end your day with Alice for long-term benefits and immediate effects

Customer review | “Absolutely love: I love how these make me feel! It’s a super subtle mood booster that has helped me with my anxiety and has made life a little more fun. My bf and I tried it together and we enjoyed it so much! Highly recommend!” – Mika C. (Read more reviews.)

5. Thorne

Best For | Greens powder
Active Ingredients | Chaga mushroom, Lion’s Mane mushroom, Maitake mushroom, Reishi mushroom, Shiitake mushroom
Contains Caffeine | Yes
Prices Starting At | $42

Thorne’s Daily Greens Plus is more than your standard greens powder – it pairs nutrient-dense supergreens with a surprisingly robust lineup of functional mushrooms, matcha, spirulina, moringa, and kelp. Its mushroom blend brings ingredients like Lion’s Mane and Chaga to the mix, which are used to support cognitive function, memory, focus, immune health, and the body’s response to everyday stress. The formula also layers in adaptogens, antioxidants, and nutrients aimed at supporting cellular energy, physical endurance, recovery, and healthy aging, making it feel more like an all-in-one wellness boost than a basic scoop of greens. And because Thorne lists every ingredient and its amount rather than hiding anything behind a proprietary blend, this supplement is a thoughtfully transparent way to pack in all the ingredients you want into a simple, daily drink.

Customer review | “I trust it precisely because of the taste. It’s not sweet like some others I’ve tried, and it even has spice (heat) to it, which tells me the radishes are present. It’s great as a meal replacement (breakfast for me). Leaves me feeling full for a long while. I don’t expect something that tastes amazing, because the focus is something packed with the right stuff. This has become a staple of my routine” – Ross (Read more reviews.)

6. MUD\WTR

Best For | Mushroom coffee alternative
Active Ingredients | Lion’s Mane, Cordyceps, Chaga, Reishi, Chai, Cacao
Contains Caffeine | Yes
Prices Starting At | $40

Need to lock in? MUD/WTR has amassed a devoted group of fans for transforming the way people drink caffeine. Their chai-based blends contain a gentle dose of caffeine combined with organic cacao, ayurvedic herbs, and functional mushrooms for focus without the crash. By supplementing the fraction of caffeine found in coffee with mushrooms and herbs, MUD/WTR boosts your brain power while also healing your body from within, instead of sabotaging your sleep and mood. Their overall goal is to help you “change your mind” by unlocking your best brain power to change your life. Plus, their Matcha, Turmeric (for full-body balance), and Rooibos (to promote rest) blends have joined the lineup to provide a drink for everyone at any time of day.

Editor review | “Mud is also not nearly as harsh on my stomach [as coffee] and doesn’t suppress my appetite as much! Overall, it’s a tasty drink (when sweetened a little), and I can certainly see it becoming a regular part of my routine.” (Read our full-length review of MUD/WTR here!)

7. Anima Mundi Herbals

Best For | Balancing hormones
Active Ingredients | Reishi, Chaga, Cordyceps, Shiitake and Maitake, Cacao
Contains Caffeine | No
Prices Starting At | $25

Anima Mundi Herbals has a range of adaptogenic supplements for everything. The brand combines mushrooms with thoughtful ingredients into formulas that you can take in either powder or tincture form. Made for overall health, these supplements support stress reduction both mentally and physically — lowering your cortisol, chilling you out, and changing how you think and feel for the better. These adaptogenic mushrooms combine into the ultimate synergistic combos to get the most out of functional fungi in each product. Plus, many of these are actually tasty, especially the cacao supplement for immortality, which is delicious on everything — from scoops in your smoothies to a garnish over your dessert.

Customer review | “Magick in jars: The powders are so fine and they hit fast! I have noticed a slow change in my mental health and how I respond to stress.” – Ayana M. (Read more reviews.)

8. Plant People

Best For | Affordable
Active Ingredients | Organic Cordyceps Mushroom Extract, Organic Lions Mane Mushroom Extract, L-theanine
Contains Caffeine | No
Prices Starting At | $20

Made by doctors to combine traditional medicine with botanical intelligence, Plant People gives you the best of both worlds — innovative formulas with ancient wisdom. Their mushroom supplements are targeted, fast-acting solutions to specific lifestyle goals that also provide lasting benefits to your health, and all for budget-friendly prices. Bundle up for supplements that support every part of your day: Sleep, stress, energy, pain, allergies, immunity, and more.

Customer review | “Best start to the day: Wonder Day is a no brainer!  My husband started taking over mine so I bought more and now it’s how we both start our day.  Love the flavor and texture.  Big improvement to our overall day.” – Susan (Read more reviews.)

9. Moon Juice

Best For | Holistic health (and beauty)
Active Ingredients | Cordyceps, Reishi, Chaga
Contains Caffeine | No
Prices Starting At | $27

Moon Juice is known for its self-care supplements that support everything from beauty to sex. Their mushroom powders are carefully crafted blends that help you get the most out of our botanical friends. Their supplements help our bodies adapt to stress and bring us to homeostasis. With your body and mind centered, you can counteract the effects of stress, brain fog, and exhaustion. Farmed from the most actively dense part of the mushroom, these super mushrooms are easy for your body to absorb thanks to the brand’s commitment to bioavailability. With third-party testing and clinically proven formulas, Moon Juice makes sure that doses are anything but random — check out the product pages to get full transparency on ingredient sourcing and explanations for each formula.

Customer review | “Great Substitute For Coffee!: I love these Moon Juice powders. Every morning I combine Chaga, Brain Dust and Power Dust together and add a teaspoon of honey for a warm and delicious healthy drink. I have brain cancer and i feel it has helped me maintain energy and focus while going through chemotherapy treatment.” – Julie S. (Read more reviews.)

10. Organic Olivia

Best For | Immune boosting
Active Ingredients | Cordyceps, Reishi, Shiitake, Turkey Tail, Agaricus blazei
Contains Caffeine | No
Prices Starting At | $48

Take this supplement from Organic Olivia daily for year-round protection. While it supports your overall health, Immune Shroom’s five mushroom formulation invigorates your body’s innate immune cells. This probiotic combination of Reishi, Cordyceps, Turkey Tail, Shiitake, and Agaricus blazei provides variety while also focusing on immunity. Mushrooms are unique in the way they support immunity. They promote an active and engaged immune response with a focus on balance. It works especially hard during allergy and cold/flu season but also offers support year-round. Its probiotic benefits also help balance the gut microbiome — which contributes to the wellbeing of the immune system.

Customer review | “Teacher approved: Absolutely loved it!! as a teacher I am always around lots of people and honestly there’s always stress. This gave me the extra boost I needed during winter months. about to restock!” – Jacqueline M (Read more reviews.)

Langa Chinyoka is a Contributing Editor at The Good Trade. She is a writer and strategist based in Los Angeles.