Tracing the Genetic Footprints of the UK National Health Service


The establishment of the UK National Health Service (NHS) in July 1948 was one of the most consequential health policy interventions of the twentieth century, providing universal and free access to medical care and substantially expanding maternal and infant health services. In this paper, we estimate the causal effect of the NHS introduction on early-life mortality and we test whether survival is selective. We adopt a regression discontinuity design under local randomization, comparing individuals born just before and just after July 1948. Leveraging newly digitized weekly death records, we document a significant decline in stillbirths and infant mortality following the introduction of the NHS, the latter driven primarily by reductions in deaths from congenital conditions and diarrhea. We then use polygenic indexes (PGIs), fixed at conception, to track changes in population composition, showing that cohorts born at or after the NHS introduction exhibit higher PGIs associated with contextually-adverse traits (e.g., depression, COPD, and preterm birth) and lower PGIs associated with contextually-valued traits (e.g., educational attainment, self-rated health, and pregnancy length), with effect sizes as large as 7.5% of a standard deviation. These results based on the UK Biobank data are robust to family-based designs and replicate in the English Longitudinal Study of Ageing and the UK Household Longitudinal Study. Effects are strongest in socioeconomically disadvantaged areas and among males. This novel evidence on the existence and magnitude of selective survival highlights how large-scale public policies can leave a persistent imprint on population composition and generate long-term survival biases.

Here is the link, via S.



Source link

  • Related Posts

    Japan, South Korea Nuclear Operators Get US Ex-Im Bank Support

    John Jovanovic, chairman of the Ex-Im Bank, said the transactions will help support industries “that are central to America’s long-term economic and strategic strength,” while supporting the development of secure,…

    Trump Rejects Deal With Iran on Current Terms as War Rages On

    (Bloomberg) — President Donald Trump said Iran is ready to make a deal to end the war but the US wants better terms, signaling no let up in a conflict…

    Leave a Reply

    Your email address will not be published. Required fields are marked *

    You Missed

    Executive producer on The Simpsons says ‘never say never’ regarding a Hit & Run revival, even if he prefers the 2007 game

    Executive producer on The Simpsons says ‘never say never’ regarding a Hit & Run revival, even if he prefers the 2007 game

    Letters: Shut down the hate before it’s too late

    Bumble is the latest dating app to add an AI assistant

    Bumble is the latest dating app to add an AI assistant

    Iran and the United States: A Long History of Antagonism

    “We are all wearing Florsheims now”, plus other funny posts, Paralympic Catch-up, Carney Hat Trick, TrumpWatch and Animal Crackers

    “We are all wearing Florsheims now”, plus other funny posts, Paralympic Catch-up, Carney Hat Trick, TrumpWatch and Animal Crackers

    Fliers running into long lines, travel headaches amid partial government shutdown

    Fliers running into long lines, travel headaches amid partial government shutdown