In the fifth and final season, it’s Homelander’s world, completely subject to his erratic, egomaniacal whims. Hughie, Mother’s Milk, and Frenchie are imprisoned in a “Freedom Camp.” Annie struggles to mount a resistance against the overwhelming Supe force. Kimiko is nowhere to be found. But when Butcher reappears, ready and willing to use a virus that will wipe all Supes off the map, he sets in motion a chain of events that will forever change the world and everyone in it. It’s the climax, people. Big stuff’s gonna happen.

Most of the main cast is returning for the final season, and we’ll also see the return of Soldier Boy (Jensen Ackles), aka Homelander’s daddy, revealed in the S4 finale mid-credits scene to be alive and chilling out in cryostorage. In addition, Jared Padalecki will join the cast in an as-yet-undisclosed role. This season will also feature several characters from Gen V: Jordan (London Thor), Marie (Jaz Sinclair), Emma/Little Cricket (Lizze Broadway), Cate (Maddie Phillips), Sam (Asa Germann), and Annabeth (Keeya King).

The first two episodes of The Boys’ fifth and final season premiere on April 8, 2026, on Prime Video, with new episodes airing each week through May 20, 2026.