Longtime Big Ten rivals will meet on Sunday on CBS and Paramount+ when the Purdue Boilermakers visit the Ohio State Buckeyes. No. 8 Purdue (22-6, 12-5 Big Ten) has won six of its last seven but dropped its last contest, 76-74, to Michigan State on Thursday. Ohio State (17-11, 9-8 Big Ten) is coming off back-to-back losses, including a Wednesday loss to Iowa, 74-57. Ohio State leads the all-time series 34-30.

Tipoff is at 1:30 p.m. ET from the Value City Arena in Columbus, Ohio. The Buckeyes have won the last two matchups, each coming by 4 or fewer points. The Boilermakers are 6.5-point favorites in the latest Ohio State vs. Purdue odds, while the over/under for total points scored is 150.5. Purdue is at -289 on the money line (risk $289 to win $100). Before making any Purdue vs. Ohio State college basketball picks, check out the men’s college basketball predictions and betting advice from the SportsLine Projection Model.

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The SportsLine Projection Model simulates every college basketball game 10,000 times and it enters Week 17 on a sizzling 11-1 run on its top-rated over/under college basketball picks dating back to last season, and is on an 20-11 run on top-rated CBB side picks. Anyone following its college basketball betting advice at sportsbooks and on betting apps could have seen strong returns.

Now, the model has simulated Purdue vs. Ohio State 10,000 times and just revealed its coveted men’s college basketball picks and betting predictions. You can head to SportsLine now to see the model’s picks. Here are several men’s college basketball odds and men’s college basketball betting lines for Ohio State vs. Purdue:

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Top Ohio State vs. Purdue predictions

SportsLine’s model has simulated Purdue vs. Ohio State 10,000 times and is going Over on the total (150.5 points). Each of the last three contests for the Boilermakers have eclipsed the total. Additionally two of Purdue’s last three road games have gone over, while the Over is 4-3 for Ohio State over its last four home matchups. For the season, Ohio State games are averaging 152.6 combined points.

Both squads rank in the top six of the Big Ten in points per game. Purdue has one of the sport’s most efficient offenses, ranking third in the country in assists but posting the ninth-fewest turnovers. Meanwhile, OSU has a go-to guy in Bruce Thornton, whose 20 ppg are fifth-most in the conference. He is projected to be one of eight total players with at least a dozen points as the Over hits 70% of the time.

How to make Purdue vs. Ohio State picks

The model also says one side of the spread hits 60% of the time. You can only see that pick at SportsLine.

So who wins Ohio State vs. Purdue, and which side of the spread hits in 60% of simulations? Visit SportsLine now to see which side of the Purdue vs. Ohio State spread to back, all from the advanced model that has simulated this game 10,000 times, and find out.