Sen. Cindy Hyde-Smith has fended off a Republican primary challenger and will advance to the general election in Mississippi, NBC News projects.

With 3% of the expected vote in, Hyde-Smith was at 83%, compared to 17% for physician Sarah Adlakha.

Hyde-Smith’s Democratic opponent for November has yet to be determined, with three candidates competing in that party’s primary, including district attorney Scott Colom.

President Donald Trump endorsed Hyde-Smith ahead of Tuesday’s primary, but she still faced a challenge from Adlakha, who largely self-funded her campaign.

Adlakha launched ads Hyde-Smith of being beholden to special interests, while Hyde-Smith accused Adlakha of being a Chicago liberal and touted her endorsement from Trump.

The primary did force Hyde-Smith to spend some of her campaign funds, spending $2.4 million on the race as of Feb. 18, according to campaign finance reports filed with the Federal Election Commission.

Hyde-Smith is running for her second full term in the Senate. She was appointed to the seat in 2018 to replace former GOP Sen. Thad Cochran, and won a special election against former Democratic Rep. Mike Espy, who had also served as Agriculture Secretary, to serve out the rest of Cochran’s term.

Hyde-Smith won her first full term in the Senate in 2020, defeating Espy again, this time by 10 points, as Trump carried the state by 16 points.

A Democrat has not won a Senate race in Mississippi since 1982 and Trump won the state by 23 points in 2024. Ty Pinkins, who was the Democratic Senate nominee against GOP Sen. Roger Wicker in 2024, is running for Senate again, but as an independent.

But some Democrats, including Democratic Senatorial Campaign Committee Chairwoman Kirsten Gillibrand, have suggested that Colom could be a strong candidate.

It wouldn’t be the first time Hyde-Smith and Colom have clashed: the GOP senator blocked Colom’s nomination for a federal judgeship during the Biden administration.