Arizona vs. SMU prediction, odds, spread: 2026 Holiday Bowl picks from proven model



The 17th-ranked Arizona Wildcats battle the SMU Mustangs in the 2026 Holiday Bowl on Friday night. Arizona is coming off a 23-7 win at Arizona State on Nov. 28, while SMU is coming off a 38-35 loss at California on Nov. 29. The Wildcats (9-3), who finished tied for fourth at 6-3 in the Big 12 Conference, have won five in a row. The Mustangs (8-4), who tied for second in the ACC at 6-2, are 1-0 against ranked teams this season. 

Kickoff from Snapdragon Stadium in San Diego is at 8 p.m. ET. The all-time series is tied 1-1, with Arizona winning 28-6 in the last meeting in 1985. The Wildcats are 1.5-point favorites in the latest Arizona vs. SMU odds, while the over/under for total points scored is 51.5 via SportsLine consensus. Before making any SMU vs. Arizona picks, check out the college football predictions from the SportsLine Projection Model. 

New users can target the DraftKings promo code, which offers $200 in bonus bets if your $5+ bet wins:

The model simulates every FBS game 10,000 times, and it is 31-19 on its top-rated college football money-line picks since the beginning of the 2024 season. 

Now, the model has set its sights on Arizona vs. SMU. You can visit SportsLine now to see the picks. Here are the FBS college football odds and trends for SMU vs. Arizona:

Arizona vs. SMU spread

Arizona -1.5 

Arizona vs. SMU over/under

51.5 points

Arizona vs. SMU money line 

SMU -111, Arizona -107

Arizona vs. SMU picks

See picks at SportsLine

Arizona vs. SMU streaming 

Fubo (Try for free)  

New users can also check out the latest FanDuel promo code and get $250 in bonus bets at FanDuel if your $5 bet wins

How to make Arizona vs. SMU picks

After 10,000 simulations, SportsLine’s model is going Over (51.5) on the total. The Over has hit in two of the last three games for the Mustangs. 

The model has Arizona quarterback Noah Fifita passing for more than 260 yards and two touchdowns, while SMU quarterback Kevin Jennings will surpass 250 yards passing and two scores. The teams are projected to combine for 58 points as the Over clears in nearly 60% of simulations. 

The model also says one side of the spread is the better value. You can see the model’s pick at SportsLine.  

So who wins Arizona vs. SMU, and which side of the spread is the better value? Visit SportsLine now to see which side of the Arizona vs. SMU spread to jump on, all from the advanced model that’s simulated this game 10,000 times, and find out.





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