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Our editors have researched and taken the best nontoxic prenatals and clean supplements. These are our favorite formulations for supporting egg quality that use bioavailable, organic, and third-party tested ingredients.

We’re born with a lifetime supply of eggs — so while supplementation and lifestyle factors won’t contribute to producing any more, there are measures you can take to increase the quality of your reserve.

There are so many unknowns in the TTC experience, whether you’re trying naturally, with IVF, or by other means. The Google searches seem endless, and we’re swarmed with advice on social media. There’s so much that’s out of our control, but clean, well-formulated supplements like these ones can provide some support.

Why are clean fertility supplements important?

It’s one thing to say a supplement is “clean,” but it’s another to back up claims with evidence-based research and third-party testing. Often one’s fertility journey is a time when we prioritize our health the most, which is why sourcing the purest ingredients is best. That means no fillers, no additives, and simple formulations. The supplements and brands we trust have formulas made with bioavailable ingredients, no GMOs, and are always tested for purity and dosages.

What should you look for in a supplement to help support egg quality?

One ingredient you’ll notice in each of the recommended supplements below is Coenzyme Q10 or CoQ10, which is also known as a male fertility supplement that boosts sperm health and motility. This, along with other bioavailable ingredients, is there to improve your egg quality by increasing cellular energy production to divide chromosomes. Other ingredients like NAD+ and Rapamycin can help with overall cellular health and may contribute to egg quality, too.

What is the difference between egg quality support and prenatals?

Prenatal vitamins are intended for use while trying to conceive through postpartum to give you and your growing baby the necessary nutrients that might be too hard to get in your diet. Egg quality support is best for those trying to conceive, especially because it contains the fertility-boosting ingredient CoQ10 which supports mitochondrial function for healthier eggs.

Our criteria:

Our editors have researched and taken these egg quality support supplements to select the best options that use natural, effective, and clean ingredients, with input from thousands of customer reviews. We update this list regularly with emerging favorites that meet the criteria below.

• CLEAN/ORGANIC INGREDIENTS | We prioritize products made with bioavailable ingredients, meaning that they provide optimal absorption for those trying to conceive. All of the options on this list are also third-party tested to limit contaminants and ensure proper dosage. 
• EASY TO TAKE | Pills aren’t always easy to swallow, which is why we looked for supplements with gentle, no-nausea formulas that don’t demand too many pills per day.
• EXPERT APPROVED | The products we recommend are often backed by research, tested by our editorial team, and approved by OBGYNs, fertility experts, and other healthcare providers.

To fully support your fertility journey and overall wellness, make sure to review our guides to the best prenatal vitamins, fertility supplements for men and women, and women’s multivitamins.

1. WeNatal

Best for | One pill with multiple benefits
Clean ingredients | Bioavailable ingredients, vegan, non-GMO, allergen-free, free from fillers and chemical binders, Kosher certified 
Price | $65 per month with a subscription

It’s rare to find a product that has a number of benefits packed into just one pill. WeNatal delivers with Egg Quality+, a five-in-one supplement designed to help with egg quality and mitochondrial function. The company as a whole is on a mission to improve fertility for both men and women, providing supplements for both partners. Egg Quality+ is best paired with WeNatal’s prenatal vitamin, and the brand recommends spacing out each of the three pills by taking one per meal (ideally with healthy fats like avocado or olive oil, since CoQ10 is fat-soluble). 

For more peace of mind, all of WeNatal’s products are third-party tested and Egg Quality+’s science-backed ingredients are expected to help women trying to conceive over the age of 35, or those diagnosed with PCOS or unexplained fertility. Subscriptions are available at more affordable rates, starting at $65 for a monthly supply. Take note that once you are pregnant, you should stop taking this supplement, as the brand says CoQ10 hasn’t been researched extensively past the preconception phase.

Customer Review | “I have been searching for a supplement that has NAC and does not smell and taste AWFUL. I finally found it! I also love that it combines multiple things in one – less pills to take.” – Erin C. (Read more reviews) 

2. Perelel

Best for | Egg freezing and IVF
Clean ingredients | Bioavailable ingredients, gluten-free, soy-free, non-GMO
Price | $50 per month with a subscription

Founded by an OBGYN, Perelel has curated packs for each stage: TTC, pregnancy, and postpartum. The Egg Freeze Support Pack includes a women’s multivitamin, omega DHA and EPA, CoQ10 and folate, and iron ease. These four pills work together to prepare your eggs for freezing or egg retrieval before in vitro fertilization (IVF). Moms-to-be also appreciate that these packs are portable and convenient, and take the guesswork out of determining which supplements to take during this sensitive time.

The Perelel Panel is a group of medical providers, who answer frequently asked questions, too. For instance, Brian Levine, M.D., M.S., F.A.C.O.G., shared that you should start taking the pack as early as three months before you freeze your eggs. For IVF patients, Perelel adds that it’s best to use the Egg Freeze Support Pack before the egg retrieval, and then switch to the Conception Support Pack afterward.

Customer Review | “I’m working on trying to freeze my eggs and want to give myself the best odds. It was so confusing trying to figure out what supplements and how much of each you need. Perelel makes it super easy by putting everything in a pack. I also love that I can just throw it in my bag and take to work with me.” – Nicole S. (Read more reviews)

The Good Trade Partner

3. Needed

Best for | Bundled subscription plans
Clean ingredients | Bioavailable ingredients, vegan, non-GMO, gluten-free, allergen-friendly
Price | $90 for a 30-day supply

Julie Sawaya and Ryan Woodbury, two moms with backgrounds in nutrition, teamed up to create Needed, a certified B Corp with a host of supplements for women and men. The website has specific products recommended for egg freezing, most notably the Egg Quality Duo. This set combines the brand’s Egg Quality Support capsules with a CoQ10 supplement. The former can be taken three to six months before trying to conceive, and delivers bioavailable ingredients like R-alpha-Lipoic Acid to promote energy production and green tea extract to “support normal egg cell health.”

Every product at Needed begins with their team of self-described “nutrition nerds” reviewing clinical research and turning to their collective of more than 20,000 practitioners, including OBGYNs and dietitians. Along with their B Corp certification, Needed is Climate Neutral certified and a member of 1% for the Planet, meaning they donate 1% or more of their annual revenue to environmental organizations.

Customer Review | “Loving this product so far. We are a few months out from our IVF cycle, and I feel like I’m preparing my body to have good quality eggs by taking this duo. Excited for the results.” – Taylor K. (Read more reviews)

4. Bird&Be

Best for | CoQ10 booster
Clean ingredients | Bioavailable ingredients, gluten-free, vegan, no unnecessary fillers
Price | $57 per month with a subscription

Bird&Be co-founders Samantha Diamond and Breanna Hughes understand the stress involved in the trying-to-conceive journey. Their personal experiences with pregnancy loss and infertility opened their eyes to what the fertility space was lacking, which is where their supplements come in. The Female Fertility Power Prenatal Pack is a series of seven capsules addressing concerns such as protecting egg quality and supporting fetal development once you’re pregnant. For women over the age of 30, they suggest adding a CoQ10 booster, which gives you an extra 200mg (600mg total).

Bird&Be products are put through rigorous third-party testing, and this supplement pack is Clean Label Project certified, which means they adhere to California’s strict Prop 65 law. The pack is for anyone trying to conceive, but many reviewers rave about how it’s helped improve the quality of their eggs before freezing or going through IVF. Plus, everything comes in a handy, travel-friendly pack (read: no fussing with a bunch of bottles). 

Customer Review | “I’m preparing for egg freezing in a few months and I wanted to find a prenatal that covered everything I need. This was the best I could find that contained all the nutrients I was looking for, and having it in a neatly prepared package gives me peace of mind I’m not forgetting anything. I’m really grateful I found this brand and product!” – Erin C. (Read more reviews)

5. FullWell

Best for | Nausea
Clean ingredients | Bioavailable nutrients, non-GMO, allergen-friendly
Price | $96 per month with a subscription

Founder Ayla Barmmer, M.S., R.D., L.D.N., leveraged her experience as a registered dietitian, women’s health and fertility expert, and mom of two to develop FullWell. With third-party tested, non-GMO ingredients in bioavailable forms, the Women’s Fertility Trio offers a prenatal multivitamin, prenatal fish oil, and fertility booster. FullWell says to add these to your routine about three to six months before trying to conceive, or before freezing your eggs or undergoing IVF. 

The prenatal multivitamin has a whopping eight capsules per serving, but there’s good news for anyone who can hardly stomach taking pills: You can choose between original (flavorless) and lemon essence, which many say provides a citrus flavor that makes pills easier to swallow.

The company supports various nonprofits and donates 3% of all new one-time or first-time subscription order sales to the purchaser’s preferred organization. In 2025, they also donated to cleanup company 4Ocean, Black Mamas Matter Alliance, and Resolve National Infertility Association.

Customer Review | “Thank you so much! This product is absolutely worth it! I ordered the lemon essence and it was a soft lemon flavor and every easy to take!” – N.t. (Read more reviews)

Featured image is from Perelel

Blake Bakkila is a freelance writer and editor with eight years of experience covering topics including baby and parenting, food, health, pop culture, and interior design. In addition to The Good Trade, her work has appeared in the digital publications of Architectural Digest, Sunset, Good Housekeeping, and more. She highlighted the best, most game-changing baby and parenting products as the former senior commerce editor at What to Expect and BabyCenter, and she’s also held editorial positions at Good Housekeeping, Health, Real Simple, and People. Blake holds a bachelor’s in journalism from Northwestern University’s Medill School of Journalism. When she’s not typing, you can usually find her watching anything on Bravo, entertaining her son Rhode, and conducting field research on the best ice cream in Southern California.