Written by Thomas Jefferson in 1801 while he was serving as vice president (and therefore the head of the Senate), the manual influenced both houses of Congress as to how to approach order and decorum.

Glenn also took with him a 13-star flag that was used to identify General George Washington on the battlefield. Believed to be inspired by the details on the general’s uniform in 1777, Washington’s Headquarters Flag (also known as the Commander-in-Chief standard) flew with Glenn in the lead-up to the bicentennial commemorations of Washington’s death in 1799.

Both the flag and the manual, though, were reproductions. The originals are in museums and deemed too fragile and irreplaceable to risk being launched into space. The copy that Glenn flew was a 1993 reprint, and the flag was made for Glenn to fly in 1998.

Another replica flag steeped in American history was aboard the International Space Station from November 2014 through June 2015. NASA astronaut Terry Virts was provided the 15-star flag by Fort McHenry in Maryland, after it was flown over the historic site for Flag Day during the bicentennial year of the Battle of Baltimore. The original of that flag was seen by Francis Scott Key to “yet wave,” leading him to write a poem that became the US anthem, The Star-Spangled Banner, in 1814.

Nailing down the (possible) oldest

In May 1869, a 17.6-karat gold spike was used to ceremonially complete the First Transcontinental Railroad at Promontory Summit in the then-Utah Territory. Today, the site is a National Historical Park located near where Northrop Grumman builds and tests solid rocket motors for space launch vehicles.

Ninety-six years later, a replica of the Golden Spike was launched on Atlantis with the STS-38 crew.

It was another spike, however, that is believed to be the oldest Americana artifact to have flown into space.

“In honor of the 200th anniversary of the commissioning of the USS Constitution, ‘Old Ironsides,’ this copper spike, an original component of the hull of the USS Constitution, [was] flown on the United States space shuttle,” a plaque presenting the nail reads.

The spike, which was removed from the ship in 1992 and dates back to 1797, was aboard Atlantis for the entirety of the STS-71 mission, from June 27 through July 7, 1995. The mission marked the first rendezvous and docking between a NASA shuttle and the former Russian space station, Mir.

Another Constitution piece, a fragment of wood of similar age, was launched into orbit with the Hubble Space Telescope on STS-31. The piece was on loan at the US Naval Academy Museum in Annapolis, Maryland.