Just this week, Pushmeet Kohli, Google Cloud’s chief scientist, published a piece in a special AI and science issue of the journal Daedalus, writing: “We are moving toward AI that doesn’t just facilitate science but begins to do science.” With autonomous AI scientists on the horizon, it’s harder to justify massive efforts to develop super-specialized tools—even one like AlphaFold, for which DeepMind scientists won a Nobel Prize, or a potentially life-saving system like WeatherNext. It also heralds a far stranger future for science, in which humans and AI systems collaborate as peers—or AI even makes scientific progress on its own.

To be clear, Google does not appear to be abandoning its work on specialized AI for science tools. AlphaGenome and AlphaEarth Foundations, which are trained for genetics and Earth science applications respectively, were released last summer, and the newest version of WeatherNext came out in November.

What’s more, such tools remain extremely popular among scientists. Last year, for instance, Google reported that protein structure predictions from AlphaFold have been used by over three million researchers worldwide. And Isomorphic Labs, a Google subsidiary that aims to use AlphaFold and related technologies to develop new drugs, just raised a $2 billion Series B funding round.

But there are concrete signs of realignment, in both enthusiasm and resources. Last month, the Los Angeles Times reported that Google fellow John Jumper, who won the Nobel for AlphaFold, is now working on AI coding, not on science-specific AI tools. It’s not surprising that Google is assigning its best minds to the coding problem, as the company has recently taken a reputational hit because its coding tools don’t currently stand up to those offered by Anthropic and OpenAI. But it may also signal a prioritization of agentic science on Google’s part, as coding abilities are key to the success of some of those systems. 

Across the industry, agentic researcher systems are showing real potential. This week, OpenAI announced that one of their models had disproved an important mathematics conjecture—perhaps the most meaningful contribution that generative AI has made to mathematics so far, according to some mathematicians.

Importantly, the model used by OpenAI is not specialized for solving mathematical problems, or even for research; according to the company, it’s a general-purpose reasoning model in the vein of GPT-5.5. If general agents can make independent contributions to mathematical research, they might soon be able to do the same in science (though the fact that ideas in science must be verified experimentally makes it a tougher domain for AI).