Eric Dane in ‘The Ravine.’
Preview:
- Eric Dane has died at the age of 53.
- He was best known for his breakout role as Dr. Mark Sloan on Grey’s Anatomy and, more recently, for his complex portrayal of Cal Jacobs on HBO’s Euphoria.
- Over a career spanning more than three decades, he became a familiar presence on both network television and the big screen.
Eric Dane, the actor who rose to fame as the charming and complicated Dr. Mark Sloan on ‘Grey’s Anatomy’ and later captivated a new generation of viewers with his performance as Cal Jacobs on HBO’s ‘Euphoria’, has died at the age of 53.
Diagnosed with ALS last year, he had been candid about his health struggles and became a staunch champion of those with the condition.

Air Date: June 16th, 2019
Dane’s family released a statement:
“Throughout his journey with ALS, Eric became a passionate advocate for awareness and research, determined to make a difference for others facing the same fight. He will be deeply missed, and lovingly remembered always. Eric adored his fans and is forever grateful for the outpouring of love and support he’s received..”
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Eric Dane: Early Life and Breakthrough
(L to R) Mark Meachum (Jensen Ackles) and Nathan Blythe (Eric Dane) in ‘Countdown’. Photo: Elizabeth Morris © Amazon Content Services LLC.
Born November 9, 1972, in San Francisco, California, Eric William Dane discovered his passion for acting in high school. After relocating to Los Angeles to pursue his career, he began landing guest roles in popular television series throughout the 1990s and early 2000s.
His major breakthrough came in 2006 when he joined the cast of ‘Grey’s Anatomy’ as Dr. Mark Sloan. Originally introduced as a recurring character, Dane’s portrayal of the confident plastic surgeon — quickly nicknamed “McSteamy” by fans — proved so popular that he was elevated to series regular. The role cemented his status as a television heartthrob and showcased his ability to balance charisma with emotional vulnerability.
Following his departure from ‘Grey’s,’ Dane starred in TNT’s action drama ‘The Last Ship’, further demonstrating his range as a leading man in high-stakes storytelling.
Eric Dane: A Career of Reinvention
Eric Dane in ‘One Fast Move’. Photo Credit: Courtesy of Prime. © Amazon Content Services LLC.
In 2019, Dane returned to critical prominence with his role as Cal Jacobs in HBO’s ‘Euphoria.’ As the troubled patriarch navigating secrecy, identity, and control, Dane delivered a performance widely praised for its intensity and nuance. The role introduced him to a younger audience and reaffirmed his staying power in an evolving television landscape.
In addition to his television success, Dane appeared in films including ‘X-Men: The Last Stand,’ where he portrayed the mutant Multiple Man, and the romantic comedy ‘Valentine’s Day.’
Throughout his career, he navigated both professional triumphs and personal challenges, speaking candidly in interviews about struggles with health and the pressures of fame.
Eric Dane: Off Screen
Eric Dane in ‘Euphoria’. Photo: Eddy Chen/HBO.
Off camera, Dane was known for his easygoing demeanor and deep devotion to his family. He often described fatherhood as his greatest role and spoke about the importance of resilience and self-awareness.
Dane leaves behind a body of work that continues to resonate with audiences — from hospital corridors in Seattle to the fraught households of modern suburbia — and a legacy defined by talent, candor, and enduring appeal.
Eric Dane stars in ‘One Fast Move’.
Selected Movies & TV Shows Featuring Eric Dane:
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